What Is The Worst Skin Disease?

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I've always though that Harlequin Ichthyosis was the worst primarily because it affects newborns and almost always kills them.  It's a nightmare to see (I don't recommend looking for pictures on the Internet).  However, for adults, one of the worst is Scleroderma which can actually lead to death.

Source: 10 Deadly Skin Diseases

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