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Is Sunburn A Histamine Reaction?

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Yes. According to a quick google search, I found that with higher levels of exposure, there's also an inflammatory reaction. Histamine, the chemical involved in most allergic reactions, is released in the skin, along with other inflammatory substances. Blood flow is increased and the skin turns red and warm to the touch. This occurs during sun exposure, but rapidly fades. It then comes back 2 to 6 hours later, with pain, as a sunburn. Typically, it's at its worst about 12 to 24 hours after sun exposure, and the soreness lasts about 3 days. After 4 to 7 days, the outer layers of skin peel off and the redness fades. The best thing to do is to take a Benadryl every few hours (as recommended on the package) along with a Tylenol. This should subside the pain and make it more manageable until the skin heals.

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